In 1998, she became a member of the girl group Innosense. The group was an opening act for both *NSYNC and Britney Spears, and it had lukewarm success in Europe and minimal impact in the U.S. The group had a cameo in the movie Longshot before calling it quits in 2001.

After leaving Innosense, Nikki focused on acting. Her movie work includes the sequel of the Sandra Bullock thriller The Net, called The Net 2.0, and a role in the series Emerald Cove, alongside some of her fellow Mouseketeers. On television, she starred in the series North Shore on Fox and Windfall. She also has made guest appearances in Grounded for Life, Walker: Texas Ranger, Cold Case, and CSI: NY.

She dated JC Chasez of *NSYNC for several years and was mentioned by her nickname Peaches in the liner notes of the group's first American album. DeLoach is working on a sociology degree from UCLA through online classes.[citation needed]

She married Ryan Goodell, who was a member of the boyband Take 5 in September 2009.